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2026 Leukemia Institute Symposium

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Key figures

2nd

symposium organized by the Leukemia Institute

2

days of scientific exchange

400

attendees

23

Speakers

Symposium programme

  • John Dick – What makes a stem cell a stem cell and how does it go bad
  • Emmanuelle Passegué – Made to order: emergency myelopoiesis and demand-adapted myeloid cell production in health and diseases
  • Françoise Porteu – Epigenetic silencing at transposable elements preserves stress resilience and prevents HSC aging and clonal expansion
  • Lina Benajiba – Targeting the leukemic-niche crosstalk in AML
  • Alexander Waclawiczek – Heterogeneity of Leukemic Stem Cells determines treatment resistance in Acute Myeloid Leukemia
  • Diana Passaro – Vascular integration in tissue bioengineering to model the complexity of leukemia microenvironment
  • David Michonneau – Understanding steroid resistance mechanisms in GVHD
  • Marcus Buschbeck – The histone variant MacroH2A1 is a chromatin component selectively required for leukemia stem cell maintenance
  • Hugues de Thé – PML orchestrates chemotherapy response by coupling oxidative stress sensing to SUMO2 homeostasis, Myc loss and senescence
  • Jean Soulier – Stem cell dysfunction as leukemia predisposition
  • Marie Sébert – DDX41 mutations in MDS/AML, from genetic insights to clinical implication
  • Marcin Wlodarski – Clonal selection in bone marrow failure: from germline variants to somatic gene rescue
  • Brunangelo Falini – New insights in NPM1-mutated AML
  • Eunice Wang – Menin inhibitors: Current and future directions
  • Alexandre Fagnan – Regulation of type-2 myelopoiesis in normal and pathological hematopoiesis
  • Ulrich Steidl – Non-genetic stem cell heterogeneity and plasticity in normal and malignant hematopoiesis
  • Margaret Goodell – Epigenetic Mechanisms Promoting Leukemia Development
  • Kévin Rouault-Pierre – Metabolic Intervention in SF3B1-MDS
  • Chloé Baron – Leukemia-derived apelin selects endothelial niche clones to promote Tumorigenesis
  • Olivier Hermine – Transferrin receptor and leukemias
  • Nicolas Duployez (Leukemia Institute Prize Recipient) – Genomics of acute myeloid leukemia: refining disease classification, risk stratification and precision medicine
  • Nicolas Boissel – Adult acute lymphoblastic leukemia: From risk stratification to immunotherapies
  • Michel Sadelain – Taking down leukemias with CAR T cells

The symposium in video

John Dick

John Dick

Françoise Porteu

Françoise Porteu

David Michonneau

David Michonneau

Marcus Buschbeck

Marcus Buschbeck

Marie Sébert

Marie Sébert

Marcin Wlodarski

Marcin Wlodarski

Brunangelo Falini

Brunangelo Falini

Eunice Wang

Eunice Wang

Alexandre Fagnan

Alexandre Fagnan

Ulrich Steidl

Ulrich Steidl

Kevin Rouault-Pierre

Kevin Rouault-Pierre

Chloé Baron

Chloé Baron

Olivier Hermine

Olivier Hermine

Full symposium programme