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History of Hematology on the Saint-Louis Campus

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From 1940 to 1990

1945

First leukemia remission achieved by Professor Jean Bernard and his team at Saint-Louis Hospital.

1980

Professor Jean Dausset awarded the Nobel Prize for the discovery of tissue groups enabling bone marrow transplantation.

1980

International morphological classification of acute leukemias established by George Flandrin and Marie-Thérèse Daniel.

1989

World’s first umbilical cord blood transplant performed by Professor Eliane Gluckman.

From 1990 to 2000

1990

Identification of the PML gene by Professor Hugues de Thé.

1990

Treatment of acute promyelocytic leukemia with retinoic acid by Professors Laurent Degos and Pierre Fenaux.

1990

Development of national cooperative groups for the treatment of acute myeloid and lymphoid leukemias by Professor Hervé Dombret.

1998

Demonstration of the predictive value of minimal residual disease by Professors Hélène Cavé and Bernard Grandchamp.

From 2000 to 2025

2000

Development of molecular hematology at Saint-Louis, Necker, and Robert-Debré Hospitals. Understanding the molecular heterogeneity of leukemias.

2016

First French child with refractory leukemia treated with CAR-T cells at Robert-Debré Hospital by Professor André Baruchel.

2016

Understanding the heterogeneity of genetically driven aplastic anemias.

2019

Establishment of the first national multidisciplinary molecular meetings for acute leukemias.

2020

Innovative treatments for aplastic anemia associated with PNH (paroxysmal nocturnal hemoglobinuria)

2023

Creation of the Leukemia Institute, designated as a University Hospital Institute (IHU) under the France 2030 plan

Leukemia Institute News

Profile of Guillaume Andrieu, research officer in the “Normal and Pathological Lymphoid Differentiation” team led by Vahid Asnafi and Elizabeth Macyntire
Researchers

Profile of Guillaume Andrieu, research officer in the “Normal and Pathological Lymphoid Differentiation” team led by Vahid Asnafi and Elizabeth Macyntire

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Exceptional launch concert of the Leukemia Institute
Patients

Exceptional launch concert of the Leukemia Institute

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Second edition of LEUKEMIA 360
Industry partners

Second edition of LEUKEMIA 360

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Establishment of a Hemato-Oncogenetics Unit led by Professor Marie Sébert
Healthcare professionals

Establishment of a Hemato-Oncogenetics Unit led by Professor Marie Sébert

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Frequently Asked Questions

The Saint-Louis Institute, formerly known as the University Institute of Hematology (IUH), takes its name from its historic location at Saint-Louis Hospital in Paris.

Jean Bernard (1907–2006) was a leading figure in French medicine, renowned for his pioneering work in hematology.

He was one of the founders of modern hematology in France.

In 1961, he established the University Institute of Hematology (IUH), which later became the Paris Saint-Louis Leukemia Institute. His goal was to bring together fundamental research, clinical practice, and education.

Jean Dausset (1916–2009) was a French physician, immunologist, and geneticist, internationally renowned for discovering the HLA system (Human Leukocyte Antigens), a major breakthrough in immunology and transplant medicine. He was awarded the Nobel Prize in Medicine in 1980.