Symposium de l'Institut de la Leucémie 2026

Chiffres clés

2nd

symposium organisé par l’Institut de la Leucémie

2

jours d’échanges scientifiques

400

personnes présentes

23

Speakers

Jour 1 – 28/09/2026

John Dick – What makes a stem cell a stem cell and how does it go bad
Emmanuelle Passegué – Made to order: emergency myelopoiesis and demand-adapted myeloid cell production in health and diseases
Françoise Porteu – Epigenetic silencing at transposable elements preserves stress resilience and prevents HSC aging and clonal expansion
Lina Benajiba – Targeting the leukemic-niche crosstalk in AML
Alexander Waclawiczek – Heterogeneity of Leukemic Stem Cells determines treatment resistance in Acute Myeloid Leukemia
Diana Passaro – Vascular integration in tissue bioengineering to model the complexity of leukemia microenvironment
David Michonneau – Understanding steroid resistance mechanisms in GVHD
Marcus Buschbeck – The histone variant MacroH2A1 is a chromatin component selectively required for leukemia stem cell maintenance
Hugues de Thé – PML orchestrates chemotherapy response by coupling oxidative stress sensing to SUMO2 homeostasis, Myc loss and senescence
Jean Soulier – Stem cell dysfunction as leukemia predisposition
Marie Sébert – DDX41 mutations in MDS/AML, from genetic insights to clinical implication
Marcin Wlodarski – Clonal selection in bone marrow failure: from germline variants to somatic gene rescue

Jour 2 – 29/09/2026

Brunangelo Falini – New insights in NPM1-mutated AML
Eunice Wang – Menin inhibitors: Current and future directions
Alexandre Fagnan – Regulation of type-2 myelopoiesis in normal and pathological hematopoiesis
Ulrich Steidl – Non-genetic stem cell heterogeneity and plasticity in normal and malignant hematopoiesis
Margaret Goodell – Epigenetic Mechanisms Promoting Leukemia Development
Kévin Rouault-Pierre – Metabolic Intervention in SF3B1-MDS
Chloé Baron – Leukemia-derived apelin selects endothelial niche clones to promote Tumorigenesis
Olivier Hermine – Transferrin receptor and leukemias
Nicolas Duployez (Leukemia Institute Prize Recipient) – Genomics of acute myeloid leukemia: refining disease classification, risk stratification and precision medicine
Nicolas Boissel – Adult acute lymphoblastic leukemia: From risk stratification to immunotherapies
Michel Sadelain – Taking down leukemias with CAR T cells