Septembre à décembre 2025

Pathway coessentiality mapping reveals complex II is required for de novo purine biosynthesis in acute myeloid leukaemia

Pathway coessentiality mapping reveals complex II is required for de novo purine biosynthesis in acute myeloid leukaemia

Stewart, A.E., Zachman, D.K., Castellano-Escuder, P. et al.

Nat Metab 7, 2474–2488 (2025).

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Age‐adapted chemotherapy and MRD‐oriented transplant for Ph-negative acute lymphoblastic leukemia: the GRAALL-2014 trial

Age‐adapted chemotherapy and MRD‐oriented transplant for Ph-negative acute lymphoblastic leukemia: the GRAALL-2014 trial

Boissel N, Chevret S, Rigal-Huguet F, Leguay TT, Hunault M, Graux C, Chalandon Y, Delabesse E, Hicheri Y, Chevallier P, Balsat M, Pastoret C, Escoffre-Barbe M, Pasquier F, Joris M, Thiebaut A, Huynh A, Dhedin N, Lemasle E, Bonmati C, Maury S, Guillerm G, Berceanu A, Schanz U, Cluzeau T, Turlure P, Rousselot P, De Prijck B, Grardel N, Béné MC, Lafage-Pochitaloff M, Cuccuini W, Ifrah NH, Lheritier V, Asnafi V, Clappier E, Dombret H.
Blood. 2025 Oct 24
Immune intervention is dispensable for retinoic acid/arsenic therapy of murine acute promyelocytic leukemia.

Immune intervention is dispensable for retinoic acid/arsenic therapy of murine acute promyelocytic leukemia.

Esnault C, Fortin G, Qiu F, Soilihi H, Souquère S, Niwa-Kawakita M, Lanchais K, Dirami T, Pierron G, De Thé H.

Haematologica. 2025 Sep 11.

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LEF1 intragenic deletion induces a dominant-negative isoform and unveils a Wnt/β-catenin vulnerability in T-ALL

LEF1 intragenic deletion induces a dominant-negative isoform and unveils a Wnt/β-catenin vulnerability in T-ALL

Delafoy M, Bonnet MF, Lengliné E, Cieslak A, Touzart A, Balducci E, Simonin M, Lhéritier V, Dourthe ME, Heid-Picard B, Latour S, Dombret H, Rousselot P, Baruchel A, Boissel N, Andrieu GP, Asnafi V.

Blood. 2025 Dec 18;146(25):3036-3049

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VEXAS anemia is a mosaic erythroblastopenia

VEXAS anemia is a mosaic erythroblastopenia

Rodrigues F, Hardouin G, El Hoss S, Ghoul A, Gautier EF, Dussiot M, A Lizarralde-Iragorri M, Santini A, Peltier S, Amireault P, Soldan V, Miccio A, Debili M, Jachiet V, Trovati Maciel T, Rossignol J, Allemand E, Mékinian AM, Georgin-Lavialle SA Pr, Salma M, Soler E, Gleizes PE, O’Donohue MF, Kosmider O, Rodriguez MS, Hermine O.

Blood. 2025 Sep 19:blood.2025029081.

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